Additional Information

Description

Fluorouracil (5-FU) 1g/20mL is a chemotherapy medication used primarily in the treatment of various cancers, including colorectal, breast, and skin cancers. It is a potent antimetabolite that interferes with the synthesis of DNA and RNA by inhibiting thymidylate synthase, which is essential for DNA replication and repair. The medication is typically administered intravenously under the supervision of trained healthcare providers.

This injectable formulation is provided in a 20 mL vial, with each vial containing 1 gram of the active ingredient. The product is packaged in boxes of 10 vials for healthcare facility use, ensuring consistent supply and easy handling during treatment courses. Fluorouracil is known for its ability to target rapidly dividing cancer cells, making it a cornerstone in the treatment of several solid tumors.

Fluorouracil’s mechanism of action is based on its structural similarity to the nucleotides that are used in DNA synthesis. Once incorporated into the growing DNA chain, fluorouracil prevents further elongation, leading to cell death. This action makes it effective against rapidly proliferating tumor cells but can also impact normal cells, leading to common side effects such as nausea, bone marrow suppression, and mucositis.